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Updated: Apr 17, 2026
A Rat Methyl-Seq Platform to Identify Epigenetic Changes Associated with Stress Exposure
Published on: October 24, 2018
Biochemical changes in rats with different behavioral characteristics under conditions of metabolic stress
N V Kirbaeva1, S N Kulakova, V A Baturina
1Research Institute of Nutrition, Russian Academy of Medical Sciences, Moscow, Russia, n.kirbaeva@gmail.com.
Abstract:
Food deprivation is an extreme state of the functional feeding system, which is reflected in the character of changes in the activity of central and peripheral components selectively included in the system. We studied the dynamics of coenzyme Q10 levels and spectrum of omega-3 and omega-6 polyunsaturated fatty acids in the blood serum, liver, and brain as well as LPO intensity in the serum and liver in behaviorally passive and active rats under conditions of food deprivation. Our results indicate that adaptive and compensatory processes during acute metabolic stress depend on the initial behavioral characteristics of the animals.
