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Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
Published on: October 31, 2019
Two new stemphol sulfates from the mangrove endophytic fungus Stemphylium sp. 33231
Xue-Ming Zhou1, Cai-Juan Zheng1, Guang-Ying Chen1
1Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou, PR China.
Abstract:
Two new stemphol sulfates, stemphol A (1) and stemphol B (2), along with known compound stemphol (3) were isolated from the EtOAc extract of the fermentation of an endophytic Stemphylium sp. 33231. The structures of these compounds were elucidated on the basis of spectroscopic analysis. The isolated compounds exhibited potent antibacterial activities against six terrestrial pathogenic bacteria with MIC values of 0.6-10 μg ml(-1). The inhibitory activities of all compounds against five cancer cell lines were evaluated.
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Fungal Group Zygomycota
Bacterial Phylum Planctomycetes
Bacterial Phylum Actinobacteria

