Arterial stiffness and cardiac functions in patients with chronic venous disease

E Ozpelit1, M E Ozpelit, G Albayrak

  • 1Department of Cardiology, Dokuz Eylul University, School of Medicine, Izmir, Turkey - ebru.ozpelit@gmail.com.

Insights

Chronic venous disease (CVD) may impact heart and arterial function. This study found subtle changes in heart structure and arterial stiffness in CVD patients, suggesting a potential subclinical disease state.

Area of Science:

  • Cardiovascular Medicine
  • Vascular Biology

Background:

  • The venous system connects directly to the heart and arterial circulation.
  • The impact of chronic venous disease (CVD) on cardiac and arterial function is not well understood.

Purpose of the Study:

  • To investigate global left and right heart function in patients with CVD.
  • To assess arterial stiffness parameters in individuals with CVD.

Main Methods:

  • Echocardiography with Doppler and tissue Doppler (TD) parameters were used to evaluate left and right ventricular function.
  • Applanation tonometry assessed arterial stiffness.
  • Study included 48 patients with stage C4-C6 CVD and 39 healthy controls.

Main Results:

  • Patients with CVD showed slightly increased left atrial area and interventricular septum thickness.
  • Right ventricular (RV) tissue Doppler systolic velocity and TAPSE were elevated in CVD patients.
  • Arterial stiffness parameters, including central aortic pressure and pulse wave velocity, were slightly higher in the CVD group.

Conclusions:

  • CVD may be linked to a subclinical disease state affecting both the arterial system and the heart.
  • Further research is necessary to confirm this association and elucidate underlying mechanisms.
Abstract

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