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Related Experiment Video

Updated: Apr 16, 2026

A Laboratory Method to Measure Contagious Yawning in Rats
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Yawning in depression: worth looking into.

T Hensch1, A Blume2, D Böttger2

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This study found that increased yawning in depression is likely linked to antidepressant treatment, not a symptom of major depression itself. Further research is needed on yawning in untreated depression.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Major depression (MD) is linked to sleep disturbances and fatigue.
  • Yawning typically increases with sleep propensity.
  • No studies directly compare yawning frequency in MD patients versus controls.

Discussion:

  • A literature review found no studies on yawning in MD patients.
  • Antidepressant use is associated with increased yawning frequency.
  • Analysis of online depression forum data indicated yawning was reported by patients undergoing antidepressant treatment.

Key Insights:

  • Increased yawning in the context of depression is primarily associated with antidepressant treatment, not an intrinsic symptom of MD.
  • Out of 63 forum users reporting increased yawning, 62 were on antidepressants.
  • Yawning was predominantly described as a side effect of medication.

Outlook:

  • Investigate yawning frequency in untreated MD patients.
  • Determine if yawning can serve as a predictor for depression treatment outcomes.
  • Explore the relationship between yawning, tonic hyperarousal, and antidepressant efficacy.