Related Experiment Video
Updated: Apr 16, 2026

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
Published on: February 18, 2022
Molecularly imprinted polymer nanomaterials and nanocomposites: atom-transfer radical polymerization with acidic
Zeynep Adali-Kaya1, Bernadette Tse Sum Bui, Aude Falcimaigne-Cordin
1Enzyme and Cell Engineering Laboratory, Compiègne University of Technology, CS60319, Rue Roger Couttolenc, 60205 Compiègne (France) http://www.utc.fr/mip.
Abstract:
Molecularly imprinted polymers (MIPs) are artificial receptors which can be tailored to bind target molecules specifically. A new method, using photoinitiated atom-transfer radical polymerization (ATRP) for their synthesis as monoliths, thin films and nanoparticles is described. The synthesis takes place at room temperature and is compatible with acidic monomers, two major limitations for the use of ATRP with MIPs. The method has been validated with MIPs specific for the drugs testosterone and S-propranolol. This study considerably widens the range of functional monomers and thus molecular templates which can be used when MIPs are synthesized by ATRP, as well as the range of physical forms of these antibody mimics, in particular films and lithographic patterns, and their post-functionalization from living chain-ends.
Related Concept Videos
Radical Chain-Growth Polymerization: Overview
Radical Chain-Growth Polymerization: Mechanism
Anionic Chain-Growth Polymerization: Overview
Olefin Metathesis Polymerization: Overview
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
Cationic Chain-Growth Polymerization: Mechanism
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...

