Applications of tunable resistive pulse sensing

Area of Science:

• Colloid and Surface Science
• Nanotechnology
• Biotechnology

Background:

• Tunable resistive pulse sensing (TRPS) is a versatile technique for characterizing submicron colloidal particles.
• Its application has expanded significantly with the growing importance of nanomedicine and biotechnology.

Purpose of the Study:

• To provide a comprehensive guide to the characteristics and applications of TRPS in recent research.
• To highlight the maturation of TRPS and its role in studying submicron colloids.

Main Methods:

• TRPS measurements of particle size, concentration, and charge.
• Analysis of diverse sample types including extracellular vesicles, drug delivery particles, and biological entities.

Main Results:

• TRPS is effectively applied across various fields, including nanomedicine, biotechnology, and food science.
• Extracellular vesicle analysis using TRPS is a rapidly growing area.
• Protocols for TRPS measurements and associated analysis techniques have been established.

Conclusions:

• TRPS is a mature and increasingly vital technique for submicron colloid characterization.
• Its applications are expanding into critical areas like nanomedicine and extracellular vesicle research.