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Ginkgo Biloba extract for angina pectoris: a systematic review
1Graduate School, Beijing University of Chinese Medicine, Beijing, 100029, China.
Chinese Journal of Integrative Medicine
|March 10, 2015
Summary
Ginkgo Biloba extract shows potential benefits for angina pectoris patients, improving symptoms and ECG readings when combined with routine Western medicine. However, low-quality trials necessitate further research for definitive conclusions on its efficacy and safety.
Area of Science:
- Cardiovascular Medicine
- Integrative and Complementary Medicine
Background:
- Angina pectoris is a common cardiovascular condition requiring effective treatment.
- Ginkgo Biloba extract is a traditional herbal remedy with potential therapeutic properties.
Purpose of the Study:
- To systematically review the efficacy and safety of Ginkgo Biloba extract in managing angina pectoris.
Main Methods:
- A comprehensive search of multiple electronic databases was conducted for randomized controlled trials (RCTs) up to December 2012.
- RCTs involving Ginkgo Biloba extract, alone or with routine Western medicine (RWM), were included.
- Data extraction and analysis followed Cochrane standards, with methodological quality assessment.
Main Results:
- Twenty-three RCTs with 2,529 patients were analyzed, revealing generally low methodological quality.
- Ginkgo Biloba extract combined with RWM demonstrated superior angina relief and electrocardiogram improvement compared to RWM alone.
- Adverse events reported included mild gastrointestinal discomfort and bitter taste.
Conclusions:
- Ginkgo Biloba extract may offer beneficial effects for angina pectoris patients.
- The current evidence is limited by the low quality of existing trials.
- High-quality clinical trials are essential to establish conclusive evidence on Ginkgo Biloba extract's efficacy and safety.
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