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Updated: Apr 16, 2026

10:16
Production and Targeting of Monovalent Quantum Dots
Published on: October 23, 2014
26.2K
Quantum dot display enhances activity of a phosphotriesterase trimer
Joyce C Breger1, Scott A Walper, Eunkeu Oh
1Center for Bio/Molecular Science and Engineering, Code 6900, U. S. Naval Research Laboratory, Washington, DC 20375, USA. igor.medintz@nrl.navy.mil.
Abstract:
Phosphotriesterase was engineered into a spontaneously forming trimer by appending it to a synthetic collagen-like triple-helix motif. Enzymatic hydrolysis of the insecticide and organophosphate nerve agent simulant paraoxon was then examined. Assembling the phosphotriesterase trimer onto semiconductor quantum dots increased the enzyme's catalytic rate and efficiency.

