[Biochemical profile of the liver of calves aged 1 to 10 days]

The biochemical hepatic profile analysis was performed in 252 neonatal Holstein-Friesian calves, aged from 1 to 10 days. The activities of glutamic oxalacetic transaminase, glutamic pyruvic transaminase, alkaline phosphatase and gamma-glutamyltransferase as well as beta-glucuronidase were estimated in blood serum and in faeces. A significant decrease in glutamic oxalacetic and glutamic pyruvic transaminase, alkaline phosphatase as well as gamma-glutamyltransferase was observed in the blood serum while in the faeces the peak of activity took place between 4-5 days for beta-glucuronidase and glutamic pyruvic transaminase and 7-8 days for glutamic oxalacetic transaminase, alkaline phosphatase and gamma-glutamyltransferase. No significant relation was found between activities of the examined enzymes in blood serum and faeces. Determination of GOT and GPT, AP, GGTP in serum may be used to describe liver function in neonatal calves. No changes in total bilirubin and total protein levels in blood serum and faeces were observed during the first 10 days of calf life.