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Sensitive fluorescence detection of lysozyme using a tris(bipyridine)ruthenium(II) complex containing multiple
Fan Zhang1, Ying-Ying Zhao, Hong Chen
1Department of Chemistry, East China Normal University, No. 500 Dongchuan Road, Shanghai 200241, P. R. China. pghe@chem.ecnu.edu.cn.
Chemical Communications (Cambridge, England)
|March 18, 2015
Abstract:
A new series of photoactive metallocyclodextrins with increased fluorescence intensity upon binding with ssDNAs/aptamers has been demonstrated to sensitively and selectively detect lysozyme. The detection mechanism relies on the formation of an aptamer-lysozyme complex, which leads to reduction of fluorescence intensity.
