Cardiac Vignette: Giant Left Atrial Appendage Aneurysm
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Updated: Apr 16, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Gary C H Gan1, Aditya Bhat1, Himanshu Desai1
1Department of Cardiology, Blacktown and Mount Druitt Hospital, Sydney, NSW, Australia.
Insights
Giant left atrial appendage (LAA), a rare condition causing chest pain, can lead to serious cardiac events. This case explores its diagnosis and management.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Diagnostics
Background:
- The left atrial appendage (LAA) is a remnant cardiac structure.
- Pathological aneurysmal enlargement of the LAA can cause myocardial infarction, atrial fibrillation, and thromboembolism.
- Giant LAA is a rare, often isolated condition.
Observation:
- A middle-aged female presented with chest pain attributed to a giant left atrial appendage.
- The case highlights the diagnostic challenges and clinical presentation of this rare condition.
Findings:
- This cardiac vignette details a rare case of giant left atrial appendage.
- It explores the natural history, diagnostic modalities, and clinical management strategies.
Implications:
- Understanding giant LAA is crucial for accurate diagnosis and effective patient management.
- Further research may elucidate optimal treatment pathways for this rare cardiac anomaly.
Background:
The left atrial appendage (LAA) is a vestigial structure located in the postero-lateral aspect of the left atrium. Aneurysmal enlargement of the LAA is pathological and can predispose to adverse events, including myocardial infarction, atrial fibrillation and systemic thromboembolism. The condition is rare and usually isolated, occurring in the absence of other cardiac defects. In this cardiac vignette, we describe a case of giant left atrial appendage in a middle aged female presenting with chest pain and explore the natural history, different investigative modalities as well as issues in clinical management of this condition.
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Aortic Regurgitation I: Introduction
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Aneurysm II: Clinical Manifestations and Diagnostic Studies

