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Updated: Apr 16, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Metal nanoparticles reduce bacterial contamination of experimental purulent wounds
I V Babushkina1, I A Mamontova, E V Gladkova
1Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Moscow, Russia, 10051968@mail.ru.
Abstract:
Bacterial contamination of experimental purulent wound in rats treated by local applications of suspension of copper and zinc nanoparticles and a combined drug based on chitosan and copper and zinc nanoparticles was evaluated. Applications of copper nanoparticle suspension and combined drug with copper and zinc nanoparticles and chitosan led to rapid elimination of the bacterial contaminant. Antibacterial activity of zinc nanoparticles was less pronounced, but the effect also differed significantly from the reference group.
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