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Restless legs syndrome in psoriasis: an unexpected comorbidity
Caroline Schell1, Ramona Schleich2, Florian Walker2
1Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research.
Restless legs syndrome (RLS) is significantly more common in psoriasis patients than in the general population. This suggests RLS screening for individuals with psoriasis may be beneficial for managing this treatable comorbidity.
Area of Science:
- Dermatology
- Neurology
- Sleep Medicine
Background:
- Restless legs syndrome (RLS) involves leg discomfort and an urge to move.
- RLS is more prevalent in conditions like lupus, multiple sclerosis, rheumatoid arthritis, and atopic dermatitis.
Purpose of the Study:
- To investigate the frequency of RLS in a German cohort of psoriasis patients.
- To explore the potential link between psoriasis and RLS due to shared disease-related stress.
Main Methods:
- A study evaluated 300 patients with psoriasis and 300 healthy controls for RLS symptoms.
- Standardized evaluations were used to assess RLS prevalence and severity.
Main Results:
- 17% of psoriasis patients reported RLS symptoms, compared to 4% in the control group.
- The average RLS score was higher in psoriasis patients with RLS (16.0 ± 9.2) than in controls with RLS (13.5 ± 7.1).
Conclusions:
- Psoriasis patients exhibit a higher frequency of Restless Legs Syndrome.
- Screening psoriasis patients for RLS is recommended as it is a treatable comorbidity.
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