Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia01:30

Dementia

728
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
728
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

2.0K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
2.0K
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

1.3K
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
1.3K
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

1.3K
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply to: Technical Comment on "Saccadic eye movement performance as an indicator of driving ability in elderly drivers".

Swiss medical weekly·2015
Same author

Saccadic eye movement performance as an indicator of driving ability in elderly drivers.

Swiss medical weekly·2015
Same author

[Traffic medicine in basic medical practice].

Therapeutische Umschau. Revue therapeutique·2011
Same author

[Driving ability and fitness to drive in people with diabetes mellitus].

Therapeutische Umschau. Revue therapeutique·2011
Same journal

[Multimodal Cardiac Imaging: New Developments for Clinical Practice].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Coronary angiography: From cardiac catheterization to advanced interventional cardiovascular imaging].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Athlete's heart: role of cardiac imaging in the prevention of sudden cardiac death].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Inflammatory Heart Disease: The Role of Multimodality Cardiac Imaging in Myocarditis and Pericarditis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

State-of-the-Art Cardiac Imaging

Therapeutische Umschau. Revue therapeutique·2026
See all related articles

Related Experiment Video

Updated: Apr 16, 2026

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects
11:12

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

18.0K

[Automobile driving capacity in dementia].

Rolf Seeger1

  • 1Verkehrsmedizin und Forensische Psychiatrie, Institut für Rechtsmedizin der Universität Zürich.

Therapeutische Umschau. Revue Therapeutique
|March 21, 2015
PubMed
Summary
This summary is machine-generated.

Early dementia impacts driving skills, but mild cases may allow continued driving for 1-3 years. Moderate dementia precludes driving. Physician-guided on-road tests aid aptitude assessment.

More Related Videos

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

4.0K
A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

1.1K

Related Experiment Videos

Last Updated: Apr 16, 2026

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects
11:12

Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects

Published on: September 18, 2012

18.0K
Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

4.0K
A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

1.1K

Area of Science:

  • Neurology
  • Geriatrics
  • Traffic Safety

Background:

  • Dementia significantly affects driving ability, even in early stages.
  • Approximately 16,000 Swiss drivers are diagnosed with dementia annually, raising concerns about road safety.
  • Executive function deficits in early dementia can lead to dangerous driving behaviors.

Purpose of the Study:

  • To evaluate driving aptitude in individuals with early-stage dementia.
  • To determine the role of cognitive tests and on-road assessments in evaluating driving capabilities.
  • To present a practical approach for primary care physicians assessing driving fitness in dementia patients.

Main Methods:

  • Review of driving aptitude in mild versus moderate dementia.
  • Discussion of the limitations of standard cognitive screening tests (MMSE, CDT, TMT) for driving assessment.
  • Emphasis on physician-guided on-road driving tests as a practical evaluation tool.

Main Results:

  • Mild dementia does not automatically disqualify drivers; up to half may drive for 1-3 more years.
  • Moderate dementia invariably results in loss of driving aptitude.
  • Standard cognitive tests are insufficient for driving aptitude evaluation but useful for initial dementia diagnosis.

Conclusions:

  • Driving aptitude assessment must consider the underlying cause and stage of dementia.
  • Regular health check-ups for older drivers (e.g., >70 in Switzerland) offer opportunities for early dementia detection.
  • Physician-guided on-road driving tests are a valuable, cost-effective method for assessing driving fitness in uncertain cases.