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Updated: Apr 15, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Bilateral acute endophthalmitis associated with munchausen syndrome
Prethy Rao1, Ankoor R Shah, Monica M Michelotti
1*Department of Ophthalmology, Beaumont Eye Institute, Royal Oak, Michigan; †Associated Retinal Consultants, Royal Oak, Michigan; ‡Department of Ophthalmology, W.K. Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, Michigan; and §Department of Pathology, University of Michigan, Ann Arbor, Michigan.
Purpose:
Endophthalmitis is a potentially blinding intraocular infection that requires urgent intervention. Self-inflicted endophthalmitis is rare, difficult to diagnose, and requires a multidisciplinary approach for management. The purpose is to present a rare case of sequential self-inflicted acute endophthalmitis as a feature of Munchausen syndrome.
Methods:
This is a case report reviewing imaging and laboratory studies.
Results:
A 42-year-old female patient developed culture-proven acute endophthalmitis sequentially in both eyes with different bacterial strains. There was clear evidence of self-inflicted corneal puncture tracks in the right eye, and during the course of inpatient psychiatric evaluation, the patient admitted to self-inflicted ocular perforations.
Conclusion:
Patients with Munchausen syndrome often injure themselves as a method of drawing attention, sympathy, or reassurance. Although ocular injuries due to psychiatric disease are known to occur, intraocular injection as a mode of self-injury is extremely rare. A high index of suspicion must be maintained when the reported history and clinical course are inconsistent.
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