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Ionization suppression effects with condensed phase membrane introduction mass spectrometry: methods to increase the

Kyle D Duncan1, Gregory W Vandergrift, Erik T Krogh

  • 1Department of Chemistry, University of Victoria, Victoria, BC, Canada; Applied Environmental Research Laboratories (AERL), Department of Chemistry, Vancouver Island University, Nanaimo, BC, Canada.

Journal of Mass Spectrometry : JMS
|March 25, 2015
PubMed
Summary

Condensed phase membrane introduction mass spectrometry (CP-MIMS) enables direct trace analysis in complex samples. This study introduces methods to overcome ionization suppression, achieving part-per-trillion detection limits for enhanced quantitation.

Keywords:
atmospheric pressure chemical ionizationbioanalytical chemistrydirect analysiselectrospray ionizationenvironmental analysisinternal standardonlinequantitation

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