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Updated: Apr 15, 2026

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
Published on: September 19, 2013
[Morphologic changes in listeria cells under the effect of metabolites of human intestinal microflora enterococci]
Aim:
Characterization of morphologic changes in listeria cells under the effect of metabolites of human intestine microflora enterococci.
Materials And Methods:
Culture of Listeria monocytogenes 88-BK cells was cultivated in the presence of enterococci waste products (experiment) or without them (control). The samples obtained were studied by atomic-force microscopy (AFM) in contact mode using scanning probe microscope SMM-2000.
Results:
The character of morpho-functional reaction of indicator culture bacterial cells allows to assume the presence of cationic anti-microbial peptides with membrane-lytic mechanism of action in 30% of the studied enterococci strains.
Conclusion:
The use of atomic-force microscopy allows to detail the mechanisms of anti-microbial activity of bacteriocins of intestine microflora microorganisms against target bacteria under close to native conditions.
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