Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

1.4K
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
1.4K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

6.4K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
6.4K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

5.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.9K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

2.9K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.9K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

4.6K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.6K
Hormones Regulating Blood Glucose01:16

Hormones Regulating Blood Glucose

9.0K
Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...
9.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multinational Consensus: Insulin Initiation with Insulin Degludec/Aspart (IDegAsp).

Advances in therapy·2018
Same author

The Berlin Declaration: A call to improve early actions related to type 2 diabetes. Why is primary care important?

Primary care diabetes·2018
Same author

Thoughts, Words, Action: The Alma-Ata Declaration to Diabetes Care Transformation.

Diabetes therapy : research, treatment and education of diabetes and related disorders·2018
Same author

Basal Insulin Inadequacy versus Failure - Using Appropriate Terminology.

European endocrinology·2018
Same author

Lessons From LEADER - All-round Leadership.

European endocrinology·2018
Same author

Beta-cell Insufficiency.

European endocrinology·2018
Same journal

Predictors of Altmetric Score in Top-Cited Orthopaedic Articles: A Bibliometric Analysis.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Carbon footprint of waste generated in orthopaedic cases in Pakistan: a pilot descriptive study.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Enhancing quotation accuracy assessment with Chatpdf - a game-changer for a century-old conundrum.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Barriers to implementing simulation-based surgical training for improving quality and safety in developing countries: A short communication.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

Intraoperative Adverse Event Reporting in Gastrointestinal Cancer Surgery: A Narrative Review on the Application of ClassIntra.

JPMA. The Journal of the Pakistan Medical Association·2026
Same journal

The Impact of Mortality and Morbidity Meetings on Quality Improvement and Patient Safety.

JPMA. The Journal of the Pakistan Medical Association·2026
See all related articles

Related Experiment Video

Updated: Apr 15, 2026

Author Spotlight: Investigating the Blood Glucose Homeostasis in Murine Brain Using a Cost-Effective Hyperglycemic And Hypoglycemic Clamp Technique
07:35

Author Spotlight: Investigating the Blood Glucose Homeostasis in Murine Brain Using a Cost-Effective Hyperglycemic And Hypoglycemic Clamp Technique

Published on: January 26, 2024

2.4K

Hypoglycaemia in diabetes.

Sanjay Kalra

    JPMA. the Journal of the Pakistan Medical Association
    |April 1, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Hypoglycaemia, a common diabetes complication, is often fatal but preventable. This review covers causes, risk factors, and management strategies for iatrogenic hypoglycaemia in diabetes.

    More Related Videos

    Improving IV Insulin Administration in a Community Hospital
    12:08

    Improving IV Insulin Administration in a Community Hospital

    Published on: June 11, 2012

    19.5K
    Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
    06:21

    Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

    Published on: April 7, 2023

    2.3K

    Related Experiment Videos

    Last Updated: Apr 15, 2026

    Author Spotlight: Investigating the Blood Glucose Homeostasis in Murine Brain Using a Cost-Effective Hyperglycemic And Hypoglycemic Clamp Technique
    07:35

    Author Spotlight: Investigating the Blood Glucose Homeostasis in Murine Brain Using a Cost-Effective Hyperglycemic And Hypoglycemic Clamp Technique

    Published on: January 26, 2024

    2.4K
    Improving IV Insulin Administration in a Community Hospital
    12:08

    Improving IV Insulin Administration in a Community Hospital

    Published on: June 11, 2012

    19.5K
    Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
    06:21

    Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

    Published on: April 7, 2023

    2.3K

    Area of Science:

    • Endocrinology
    • Metabolic Diseases
    • Diabetes Management

    Background:

    • Hypoglycaemia is a frequent and potentially fatal complication in diabetes management.
    • Understanding its causes and risk factors is crucial for patient safety.

    Purpose of the Study:

    • To review recent advances in understanding iatrogenic hypoglycaemia in diabetes.
    • To present a framework for classifying causative and risk factors.
    • To discuss prevention and management strategies.

    Main Methods:

    • Literature review of recent advances in diabetes management.
    • Analysis of clinical risk factors associated with hypoglycaemia.
    • Classification framework development.

    Main Results:

    • Identified key causes and clinical risk factors for iatrogenic hypoglycaemia.
    • Proposed a framework for assessing these factors.
    • Summarized non-pharmacological and pharmacological interventions.

    Conclusions:

    • Iatrogenic hypoglycaemia in diabetes is a significant concern but manageable.
    • A systematic approach to identifying and addressing risk factors is essential.
    • Effective prevention and management strategies are available.