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Updated: Apr 15, 2026
IgY Technology: Extraction of Chicken Antibodies from Egg Yolk by Polyethylene Glycol PEG Precipitation
Published on: May 1, 2011
Polyethylene glycol antiglobulin test (PEG-AGT)
1MT(ASCP)SBB, Supervisor, IRL, American Red Cross, Lewis and Clark Region, 6616 South 900 East, Salt Lake City, UT 84121.
Abstract:
Polyethylene glycol (PEG) ws described in 1987 as a new technique for immunohematology testing. The original paper described its use in detection and identification of weakly reactive antibodies. PEG is used as an additive to enhance reactivity and to reduce incubation time when testing for unexpected antibodies. PEG can be used as an alternative to low-ionic-strength saline and whenever weak reactions are encountered.
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