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Urinary tract infections in children: knowledge updates and a salute to the future
1Departments of Urology and Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Insights
Effective management of bladder and bowel dysfunction is key to preventing urinary tract infections (UTIs). Understanding Escherichia coli pathogenesis and recurrent UTI risk factors aids in developing targeted interventions.
Area of Science:
- Urology
- Infectious Diseases
- Pediatrics
Background:
- Bladder and bowel dysfunction increase urinary tract infection (UTI) risk.
- Recurrent UTIs are often linked to antibiotic-protected intracellular reservoirs of Escherichia coli.
Unlabelled:
1. Evaluating and treating bladder and bowel dysfunction are critical in reducing the risk of urinary tract infections (UTIs). 2. The pathogenesis of Escherichia coli infections reveals that quiescent intracellular reservoirs may be antibiotic-protected sources of recurrent infections.
Objectives:
1. Review the documentation of UTI and the importance of the urine culture. 2. Understand the controversy over imaging and management of febrile UTIs in children. 3. Recognize the risk factors for recurrent UTIs and strategies for intervention. 4. Update information on the pathogenesis of E coli UTIs.
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