Related Experiment Video
Updated: Apr 15, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice
Published on: January 24, 2025
Aspects of abuse: consequences of childhood victimization
Allison M Jackson1, Katherine Deye1
1Children׳s National Medical Center, The George Washington University School of Medicine and Health Sciences, Washington, DC.
Abstract:
Childhood maltreatment is unfortunately a common occurrence in the United States, affecting 1 in 8 children annually.(1) The consequences of maltreatment can be considerable, and exact a heavy toll on the individual, family, and society. Child abuse and neglect can cause permanent, heritable changes in the body׳s response to stress, which in turn inflicts profound changes in the developing brain. While these changes allow a child to contend with a neglectful, chaotic, or possibly violent environment, they strongly influence an individual׳s behavioral, educational, physical, and mental functioning and well-being throughout his/her lifetime, long after the maltreatment has ended. As the adverse childhood experiences (ACE) studies clearly demonstrate, adult survivors of maltreatment experience significant health harms that can cause significant morbidity and contribute to early death. Further, the lifetime economic cost to society of childhood maltreatment is estimated to be $124 billion dollars.(2) The study of resilient individuals who appear to suffer fewer negative consequences of their maltreatment offers insights into possible interventions for clinical practice as well as advocacy and public policy opportunities that would begin to lessen the significant burdens of childhood maltreatment.
Related Concept Videos
Bullying
Oppositional Defiant Disorder
Diagnostic Criteria and...
Psychological and Sociocultural Causes of Schizophrenia
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...

