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Published on: May 9, 2022
Labial adhesions and outcomes of office management
Catalina Granada1, Nancy Sokkary2, Haleh Sangi-Haghpeykar1
1Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX.
Study Objective:
To evaluate clinical outcomes of labial adhesions (LA) and to examine the association between LA, lichen sclerosus (LS), eczema (ECZ), or asthma.
Design:
Retrospective study.
Setting:
Single pediatric and adolescent gynecology clinic, Houston, Texas.
Participants:
50 girls diagnosed with LA from 2006-2011.
Interventions And Main Outcome Measures:
Resolution, recurrence, single vs multiple treatments, need for surgery, and conditions such as LS, ECZ, and asthma were reviewed.
Results:
Mean age was 19.6 months (range 0-84 months), and 48% were Caucasian. Most patients were symptomatic (62%) and all 50 patients chose estrogen treatment. The majority (74%) required multiple treatments, as opposed to a single treatment (26%). Patients with multiple treatments were more likely to be severely agglutinated (P = .05) and to need manual separation after failed topical treatment (P = .08). The prevalence of asthma, LS, and ECZ was 9.8%, 7.8%, and 3.9% respectively. There was no association between LS, ECZ, or asthma, and number of treatments. Both asthma (N = 3; 8%), and LS (N = 2; 5%) were present among the severe agglutinated group; however, this difference was not statistically significant (P values .59 and .99). No association with ECZ was seen in either group.
Conclusion:
Severe agglutination tends to be associated with need of multiple treatments and manual separation. A concurrent diagnosis of LS, ECZ, or asthma was not associated with number of treatments but there appears to be a trend towards severity of LA in patients with asthma and LS.

