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Related Experiment Video

Updated: Apr 15, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Cherubism: a case report.

Saikrishna Degala1, K P Mahesh2, Monalisha1

  • 1Department of OMFS, JSS Dental College and Hospital, JSS University, Mysore, Karnataka India.

Journal of Maxillofacial and Oral Surgery
|April 11, 2015
PubMed
Summary

Cherubism, a rare jaw condition, causes painless swelling in children, typically resolving after puberty. This case report details a 10-year-old boy

Area of Science:

  • Oral and Maxillofacial Pathology
  • Pediatric Dentistry
  • Genetics

Background:

  • Cherubism is a rare, benign fibro-osseous lesion affecting the jaw.
  • Characterized by bilateral, symmetric, painless jaw expansion, often more severe in males.
  • Typically presents in childhood and regresses post-puberty, though familial and sporadic cases exist.

Observation:

  • Presents a case of cherubism in a 10-year-old boy.
  • Highlights clinical, histological, biochemical, and radiographic features.
  • Discusses the lesion's characteristic fibrovascular tissue with multinucleated giant cells.

Findings:

  • The case illustrates typical cherubism presentation and progression.
  • Confirms the replacement of normal bone with abnormal fibrovascular tissue.
Keywords:
CherubismGiant cell lesion

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  • Demonstrates the importance of comprehensive evaluation in diagnosing cherubism.

    • Implications:

    • Enhances understanding of cherubism's clinical and pathological spectrum.
    • Provides insights for managing pediatric fibro-osseous lesions.
    • Contributes to the literature on sporadic and familial cases of cherubism.