[Biomechanical analysis of different ProDisc-C arthroplasty design parameters after implanted: a numerical...

Area of Science:

• Biomechanics
• Spinal Surgery
• Biomedical Engineering

Background:

• Cervical disc arthroplasty aims to restore motion and reduce adjacent segment disease.
• ProDisc-C is a common artificial disc used for C5-C6 spinal segments.
• Optimizing artificial disc design is crucial for long-term clinical success.

Purpose of the Study:

• To evaluate the biomechanical effects of varying ProDisc-C artificial disc curvature at the C5-C6 level.
• To analyze the influence of design modifications on range of motion and joint loading.
• To provide insights for improved artificial disc design.

Main Methods:

• Development and validation of a finite element (FE) model of the C5-C6 cervical spine segment.
• Simulation of ProDisc-C implantation with varied ball-and-socket curvature.
• Application of physiological loads including compression and pure moments (flexion-extension, lateral bending, axial torsion).

Main Results:

• ProDisc-C curvature significantly affected the range of motion in flexion/extension.
• No significant differences in motion were observed under lateral bending and axial torsion loads.
• Increased curvature reduced polyethylene stress but elevated facet joint forces and ligament tension.

Conclusions:

• Cervical artificial disc curvature is a critical design parameter influencing biomechanical response.
• Design modifications must balance motion preservation with avoidance of adverse joint/ligament loading.
• Comprehensive design strategies are essential for favorable long-term clinical outcomes in cervical arthroplasty.