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N-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor

Yasunori Miyamoto1, Fumi Sakane, Kei Hashimoto

  • 1a The Graduate School of Humanities and Sciences; Ochanomizu University ; Tokyo , Japan.

Cell Adhesion & Migration
|April 15, 2015
PubMed

Keywords:
AJ, adherens junctionEC, extracellularFox, forkhead boxFrz, frizzledGFAP, glial fibrillary acidic proteinGSK3β, glycogen synthase kinase 3βHes, hairly/enhancer of splitHh, hedgehogIP, intermediate progenitorKO, knockoutLEF, lymphocyte enhancer factorN-cadherinNPC, neural progenitor cellPar, partition defective complex proteinPtc, PachedSmo, smoothenedSox2, sry (sex determining region Y)-box containing gene 2TA cell, transient amplifying cell; ZO-1, Zonula Occludens-1.TCF, T-cell factoraPKC, atypical protein kinase Cadherens junctionapico-basal polarityiPSC, induced pluripotent stem cellneural progenitor cellsngn2, neurogenin 2shRNA, short hairpin RNAβ-catenin

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