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Updated: Apr 15, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
[The cytomorphologic characteristics of parathyroids under hyperparathyroidism]
Abstract:
The article presents the results of intravital studying of cytomorphologic characteristics of elements of tissue of parathyroids obtained under thin-needle aspiration biopsy in patients with hyperparathyroidism. The analysis was applied to 84 fragments of cell material from node formations in projection of anatomic localization of parathyroids and in projection of lobes and isthmus of thyroid gland. The cytologic preparations colored with Pappenheim azure-eosin staining were analyzed using light microscopy. The results were compared with data of histological study of post-operation material. The following cytomorphologic signs of tissue of parathyroids under hyperparathyroidism: heterogeneity of population of cells of glandular epithelium--presence of main (dark, light) and oxyphilous parathyrocytes with prevalence of main parathyrocytes; occurrence of expressed intracellular contacts in groupings of parathyrocytes with formation of rosette-strand like structures or compact assemblies as well as occurrence of dark polymorphic granules positioned in cytoplasm of epithelium cells and intercellular medium.
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