Cognitive behavioral therapy for adults with attention-deficit hyperactivity disorder: study protocol for a...

Area of Science:

• Psychiatry
• Clinical Psychology
• Neuroscience

Background:

• Attention-deficit hyperactivity disorder (ADHD) persists into adulthood for approximately half of diagnosed children, causing significant functional impairments.
• Adult ADHD is associated with adverse outcomes like academic/occupational failures and substance abuse, imposing a societal burden.
• While cognitive behavioral therapy (CBT) is a recommended treatment, its efficacy and the role of booster sessions in adult ADHD remain under-investigated, particularly in China.

Purpose of the Study:

• To evaluate the efficacy of a 12-week course of CBT for adult ADHD.
• To explore the effectiveness of monthly booster sessions following initial CBT in reducing recurrence and improving long-term outcomes for adult ADHD patients.
• To provide evidence for CBT's utility in the Chinese population and inform clinical practice.

Main Methods:

• A three-armed randomized controlled trial involving adult ADHD outpatients from Peking University Sixth Hospital.
• Participants were randomized into three groups: CBT with booster sessions, CBT alone, and a waiting list control.
• Primary endpoints assessed ADHD core symptoms at 12 and 24 weeks, with secondary endpoints including emotional regulation, executive function, self-esteem, quality of life, and fMRI data.

Main Results:

• The study is the first to investigate CBT booster sessions for adult ADHD.
• Results are anticipated to demonstrate the efficacy of CBT for adult ADHD in China.
• Findings regarding booster sessions are expected to offer valuable insights for clinical application and long-term patient management.

Conclusions:

• This trial represents a novel investigation into the impact of booster sessions within CBT for adult ADHD.
• The findings are expected to bolster the evidence base for CBT's effectiveness in treating adult ADHD within the Chinese context.
• Positive outcomes from booster sessions could significantly enhance long-term treatment strategies and patient well-being.