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Updated: Apr 14, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration
Published on: May 25, 2012
Tissue augmentation and replacement of a heel fat pad with a decellularized sterile human dermal matrix
1UCSD Medical Center, San Diego, CA;
Abstract:
The use of xenografts and allografts has been primarily direct- ed at chronic wounds and tendon repair. Currently, there are no known devices in this category that can successfully be used to augment tis- sue. Patients who have undergone trauma and subsequent surgery, par- ticularly in weight-bearing areas, may experience pain with pressure or ambulation at the site. This report illustrates the use of an allograft for tissue augmentation in a young individual who was involved in a motor vehicle accident resulting in loss of the plantar fat pad. An allograft was successfully used for tissue replacement, thereby reducing pain and facilitating weight-bearing ambulation. .

