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Fatal outcome of echovirus 7 infection
D O Ho-Yen1, R Hardie, J McClure
1Regional Virus Laboratory, Ruchill Hospital, Glasgow, Scotland.
Scandinavian Journal of Infectious Diseases
|January 1, 1989
Summary
Disseminated echovirus 7 infection caused a fatal outcome in a 9-month-old infant. The infection led to liver failure, candidiasis, and marrow hypoplasia, possibly due to immune deficiency.
Area of Science:
- Pediatric Infectious Diseases
- Virology
- Immunology
Background:
- Echovirus 7 (E7) is a known human enterovirus.
- Disseminated viral infections can be severe in infants.
- Immune deficiencies increase susceptibility to severe infections.
Observation:
- A 9-month-old boy presented with disseminated echovirus 7 infection.
- The virus was isolated from the liver and spleen.
- The patient experienced hepatic failure, candidiasis, and marrow hypoplasia.
Findings:
- Echovirus 7 infection was confirmed as the cause of death.
- Hepatic failure was a significant complication.
- Possible underlying immune deficiency may have contributed to the severity.
Implications:
- This case highlights the potential severity of echovirus 7 infections in infants.
- Early diagnosis and management of viral infections in immunocompromised infants are crucial.
- Further research into the role of immune status in echovirus pathogenesis is warranted.