Recurrent childhood PRES.

Area of Science:

• Neurology
• Pediatrics
• Radiology

Background:

• Posterior reversible encephalopathy syndrome (PRES) is a neurological condition.
• Recurrent episodes of PRES are not well-documented in pediatric populations.

Observation:

• This study retrospectively analyzed 32 children diagnosed with PRES.
• Four pediatric patients experienced recurrent PRES episodes.
• Recurrent cases were associated with diverse underlying conditions, including Chediak-Higashi syndrome, ALL, chronic renal disease, and post-renal transplant status.

Findings:

• Recurrent PRES in children is frequently associated with repeated hypertension.
• Other contributing factors include underlying diseases, immune disorders, and treatment side effects.
• One patient with recurrent PRES died from multiorgan failure, while three recovered without neurological deficits.

Implications:

• Recognizing the potential for recurrent PRES is crucial for pediatricians and neurologists.
• Close monitoring of blood pressure and underlying conditions is vital in patients with a history of PRES.
• Further research into the specific mechanisms and management of recurrent pediatric PRES is warranted.