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Recurrent childhood PRES.

Fuldem Yildirim Donmez¹, Ahmet Muhtesem Agildere

¹Department of Radiology, Baskent University Medical Faculty, 44. Sokak No: 11/8, Bahcelievler, Ankara, Turkey, fuldemyildirim@yahoo.com.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

|April 21, 2015

Summary

Recurrent posterior reversible encephalopathy syndrome (PRES) can occur in children, often linked to high blood pressure and various underlying conditions. Understanding these triggers is key to managing repeated episodes.

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Area of Science:

Neurology
Pediatrics
Radiology

Background:

Posterior reversible encephalopathy syndrome (PRES) is a neurological condition.
Recurrent episodes of PRES are not well-documented in pediatric populations.

Observation:

This study retrospectively analyzed 32 children diagnosed with PRES.
Four pediatric patients experienced recurrent PRES episodes.
Recurrent cases were associated with diverse underlying conditions, including Chediak-Higashi syndrome, ALL, chronic renal disease, and post-renal transplant status.

Findings:

Recurrent PRES in children is frequently associated with repeated hypertension.
Other contributing factors include underlying diseases, immune disorders, and treatment side effects.
One patient with recurrent PRES died from multiorgan failure, while three recovered without neurological deficits.

Implications:

Recognizing the potential for recurrent PRES is crucial for pediatricians and neurologists.
Close monitoring of blood pressure and underlying conditions is vital in patients with a history of PRES.
Further research into the specific mechanisms and management of recurrent pediatric PRES is warranted.