Second digit and fourth digit ratio--an adjunct tool to predict obstructive sleep apnea

Area of Science:

• Endocrinology
• Sleep Medicine
• Anthropometry

Background:

• Obstructive sleep apnea (OSA) is a prevalent sleep disorder with significant health risks.
• Digit ratio (2D:4D) is a marker for prenatal and adult testosterone levels.
• Investigating novel predictors for OSA is crucial for early detection and management.

Purpose of the Study:

• To examine the relationship between the 2D:4D ratio and obstructive sleep apnea.
• To determine if 2D:4D can serve as a predictive marker for OSA.

Main Methods:

• A study involving 290 participants aged 20-45 years.
• Measurement of digit ratio (2D:4D) for both sexes.
• Assessment of OSA-related parameters including Berlin score, Epworth score, neck circumference (NC), and waist-hip ratio (WHR).

Main Results:

• A significant negative correlation was found between 2D:4D ratio and OSA indicators.
• Lower 2D:4D ratios were associated with higher Berlin and Epworth scores.
• 2D:4D showed a negative correlation with neck circumference and waist-hip ratio.

Conclusions:

• A lower 2D:4D ratio is associated with an increased risk of developing obstructive sleep apnea.
• The 2D:4D ratio may function as an adjunctive tool for OSA prediction.