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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
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 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
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Related Experiment Video

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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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Venous claudication in Behçet's disease.

Serdal Ugurlu1, Emire Seyahi1, Veysel Oktay2

  • 1Division of Rheumatology, Department of Medicine, Cerrahpaşa Medical Faculty, University of Istanbul, Istanbul, Turkey.

Journal of Vascular Surgery
|April 26, 2015
PubMed
Summary

Venous claudication is a frequent symptom in Behçet's disease (BD) patients with lower extremity venous thrombosis (LEVT), affecting up to one third. This condition impairs walking capacity in about 10% of these individuals.

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Area of Science:

  • Vascular Medicine
  • Rheumatology
  • Nephrology

Background:

  • Venous claudication is notably more prevalent in Behçet's disease (BD) patients.
  • Previous research suggested a link between venous claudication and lower extremity venous thrombosis (LEVT) in men with BD.

Purpose of the Study:

  • To prospectively reassess the occurrence of venous claudication in BD patients.
  • To evaluate the impact of LEVT on the prevalence and severity of venous claudication.

Main Methods:

  • A prospective study involving 61 BD patients with LEVT, 40 BD patients without vascular involvement, and 56 healthy controls.
  • Assessment of venous claudication using a standardized questionnaire and a 10-minute treadmill exercise test.
  • Measurement of ankle-brachial pressure indices to rule out peripheral arterial disease.

Main Results:

  • 34% of BD patients with LEVT reported venous claudication via questionnaire, compared to 5% of BD patients without vascular involvement and 0% of controls (P < .001).
  • During treadmill exercise, 21% of BD patients with LEVT experienced claudication symptoms, versus 8% of BD patients without vascular disease and 2% of controls (P = .002).
  • Six (10%) BD patients with LEVT had to discontinue the treadmill test due to claudication.

Conclusions:

  • Venous claudication is a significant and common complication in BD patients with LEVT, affecting up to one-third of this population.
  • The symptom can substantially impair walking capacity in approximately 10% of affected BD patients with LEVT.