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Lateralization

Lateralization

Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.

Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...

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Related Experiment Video

Updated: Apr 14, 2026

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI

Published on: November 27, 2019

Lateralisation abnormalities in obsessive-compulsive disorder: a line bisection study.

Naren Prahlada Rao¹, Rashmi Arasappa¹, Nalini Narayana Reddy¹

¹1Department of Psychiatry,National Institute of Mental Health and Neurosciences,Bangalore,Karnataka,India.

Acta Neuropsychiatrica

|April 28, 2015

Summary

This summary is machine-generated.

Obsessive-compulsive disorder (OCD) patients exhibit abnormal brain lateralization, specifically right hemisphere dysfunction, as evidenced by the line bisection task. This impaired laterality correlates with more severe OCD symptoms.

Keywords:

asymmetry laterality line bisection obsessive–compulsive disorder right hemisphere

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Area of Science:

Neuroscience
Psychiatry
Cognitive Psychology

Background:

Cerebral asymmetry is linked to psychiatric disorders.
Right hemisphere abnormalities are noted in obsessive-compulsive disorder (OCD).
Cerebral asymmetry in OCD remains under-examined.

Purpose of the Study:

To investigate anomalous cerebral asymmetry in OCD patients.
To utilize the line bisection task to assess lateralization in OCD.

Main Methods:

A cohort of 30 OCD patients and 30 matched healthy controls participated.
The two-hand line bisection (LBS) task was employed.
Analysis of covariance was used to compare LBS scores.

Main Results:

OCD patients demonstrated significantly fewer leftward line bisections.
A notable rightward deviation was observed in OCD patients compared to controls.
Impaired lateralization correlated with greater illness severity at baseline.

Conclusions:

OCD is associated with abnormal cerebral lateralization.
Evidence points to right hemisphere dysfunction in individuals with OCD.