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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Varicose veins of lower extremities, hemodynamics and treatment methods
Maciej Chwała1, Wojciech Szczeklik2, Michał Szczeklik3
1Clinical Department of Vascular Surgery, University Hospital, Kraków, Poland.
Insights
Chronic venous insufficiency affects half of adults, potentially causing serious complications. This review details its causes, traditional treatments, and the rise of minimally invasive therapies for better outcomes.
Area of Science:
- Vascular Medicine
- Phlebology
Background:
- Chronic venous insufficiency (CVI) is a prevalent vascular disorder impacting roughly 50% of the adult population.
- Untreated CVI can progress to severe complications such as venous ulceration and deep vein thrombosis.
- Understanding the epidemiology and ethiopathogenesis, including hemodynamic and microcirculatory changes, is crucial for effective management.
Discussion:
- Traditional surgical interventions for varicose veins, while effective, have limitations and contraindications.
- Minimally invasive treatments, including thermal (radiofrequency ablation, endovenous laser ablation, steam ablation) and nonthermal (sclerotherapy, echosclerotherapy, Clarivein, Sapheon) methods, are increasingly utilized.
- Each method's historical context, mechanism of action, indications, and limitations are reviewed.
Key Insights:
- Comparative studies and meta-analyses indicate a progressive shift towards minimally invasive treatment modalities.
- Minimally invasive techniques offer potential advantages in terms of patient recovery and reduced complications.
- Evidence supports the efficacy of various minimally invasive options for managing CVI.
Outlook:
- The trend favors minimally invasive approaches for chronic venous insufficiency treatment.
- Future developments are expected to refine existing minimally invasive techniques and introduce novel therapeutic strategies.
- Continued research will likely focus on long-term outcomes and comparative effectiveness of emerging CVI treatments.
Abstract:
Chronic venous insufficiency is one of the most common disorders of the vascular system, affecting approximately 50% of adults. If left untreated it can lead to a number of complications, including venous ulceration and venous thrombosis. This review paper outlines the epidemiology and ethiopathogenesis of the disease with regard to hemodynamics and microcirculation disturbances. It describes the medical treatment as well as the traditional surgical approach to varicose veins (with several modifications of this technique), and its limitations and contraindications. Furthermore, it discusses a number of new, minimally invasive treatment methods, namely thermal in form (radiofrequency ablation, endovenous laser ablation, steam ablation) and nonthermal (sclerotherapy, echosclerotherapy, Clarivein, Sapheon). For each method, there is a brief historical overview, a description of its mechanism of action, and its indications and limitations. The results of comparative studies on individual treatment methods as well as meta-analyses on this topic are briefly discussed. This paper highlights the progressive trend towards minimally invasive methods and attempts to predict the further development.
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