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Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
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Setaria digitata in advancing our knowledge of human lymphatic filariasis
A N I Perumal1, Y I N S Gunawardene2, R S Dassanayake1
1Department of Chemistry,Faculty of Science, University of Colombo,Sri Lanka.
Abstract:
Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases.
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