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Updated: Apr 13, 2026

On-Chip Crystallization and Large-Scale Serial Diffraction at Room Temperature
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Infrared imaging enhances retinal crystals in Bietti's crystalline dystrophy
Vikram S Brar1, William H Benson1
1Department of Ophthalmology, Medical College of Virginia Campus, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Abstract:
Infrared imaging dramatically increased the number of crystalline deposits visualized compared with clinical examination, standard color fundus photography, and red free imaging in patients with Bietti's crystalline dystrophy. We believe that this imaging modality significantly improves the sensitivity with which these lesions are detected, facilitating earlier diagnosis and may potentially serve as a prognostic indicator when examined over time.
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