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Updated: Apr 13, 2026
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Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
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Recognizing and managing infections in total joint arthroplasty
Wade D Aumiller1, Thomas M Kleuser
1Wade D. Aumiller is a PA student at the University of Texas Pan American in Edinburg, Tex. Thomas M. Kleuser practices orthopedic surgery in Fort Worth, Tex. The authors have disclosed no potential conflicts of interest, financial or otherwise.
Summary
Periprosthetic joint infections complicate 1-4% of joint replacements. This review covers diagnosing and treating these challenging infections to reduce patient and financial burdens.
Area of Science:
- Orthopedic surgery
- Infectious diseases
- Medical device complications
Background:
- Periprosthetic joint infections (PJIs) are serious complications following joint arthroplasty.
- PJIs affect 1% to 4% of patients undergoing joint replacement surgery.
- The rising number of joint replacements increases the clinical and financial impact of PJIs.
Purpose of the Study:
- To provide a comprehensive review of current diagnostic methods for PJIs.
- To outline effective treatment strategies for PJIs.
- To address the growing challenge posed by PJIs in joint arthroplasty.
Main Methods:
- Literature review of diagnostic techniques for PJIs.
- Analysis of established and emerging treatment protocols for PJIs.
- Synthesis of clinical evidence regarding PJI management.
Main Results:
- Early and accurate diagnosis is crucial for successful PJI management.
- Treatment often involves surgical intervention, antibiotics, or a combination.
- Multidisciplinary approaches improve patient outcomes.
Conclusions:
- Effective diagnosis and timely treatment are essential to manage periprosthetic joint infections.
- Addressing the burden of PJIs requires ongoing research and optimized clinical practice.
- This review offers guidance for healthcare professionals managing patients with PJIs.
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