Evolution of septated cavitary subretinal fluid after treatment of choroidal metastasis

An 83-year-old man presented with a 10-day history of decreased vision in the left eye. He was found to have choroidal metastases from lung adenocarcinoma that exhibited unilateral septated cavitary subretinal fluid on spectral-domain optical coherence tomography (OCT). This fluid evolved into atypical lamellar sheets after treatment with systemic chemotherapy and orbital radiation prior to resolution. This is the first description demonstrating cavitary subretinal fluid pockets on spectral-domain OCT from lung cancer; attention is given to its unusual course and proposed pathogenesis.