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[Clinical assessment for 152 total cysto-urethrectomized bladder cancers]
Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|November 1, 1989
Summary
This study analyzed 152 bladder tumor patients treated with cystourethrectomy. Advanced tumor stage and lymph node metastasis significantly reduced survival rates, highlighting the importance of clinical assessment for bladder cancer.
Area of Science:
- Urology
- Oncology
- Clinical Medicine
Context:
- Retrospective analysis of 325 bladder tumor cases treated between July 1975 and September 1987.
- Focus on 152 patients who underwent total cystourethrectomy.
- Data collected on patient demographics, tumor grade, stage, and treatment.
Purpose:
- To perform a clinical assessment of bladder tumor patients treated with total cystourethrectomy.
- To evaluate the impact of tumor grade, stage, and lymph node metastasis on survival rates.
- To investigate the relationship between macroscopic tumor appearance and patient outcomes.
Summary:
- Overall 5-year survival rate was 62%. Survival decreased significantly with higher tumor grades (G3: 55%) and advanced stages (T3b: 36%, T4: 13%).
- Lymph node metastasis was a critical prognostic factor, with a 5-year survival rate of 22% for positive nodes versus 70% for negative nodes.
- Macroscopic features like size, multiplicity, and growth pattern (papillary/nodular) were associated with survival.
Impact:
- Identifies key clinical factors influencing bladder tumor prognosis.
- Emphasizes the prognostic significance of lymph node status in bladder cancer.
- Suggests that detailed clinical assessments can improve therapeutic strategies and patient outcomes for bladder tumors.