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Microwave-assisted preparation of N-doped carbon dots as a biosensor for electrochemical dopamine detection
Yuliang Jiang1, Bingxiang Wang2, Fandian Meng3
1Key Lab of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China; School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China.
Abstract:
A new N-doped carbon dots (NCDs) could be prepared by using the microwave-assisted technique within 10 min without the need for any solvent or catalyst. The NCDs exhibited a highly sensitive electrochemical response toward dopamine (DA) in Phosphate Buffered Saline (PBS) (pH=6.5). The detection limit of DA was calculated by differential pulse voltammetry (DPV) as low as 1.2×10(-9) mol/L with a linear dynamic range of 5.0×10(-8) to 8.0×10(-6) mol/L. These results suggested that this new NCDs could be effectively used for the direct and rapid detection of trace levels of DA in human serum and urine samples.
