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Updated: Apr 12, 2026

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
Published on: October 9, 2014
Bicortical screw fixation provides superior biomechanical stability but devastating failure modes in periprosthetic
Clemens Gwinner1, Sven Märdian, Tobias Dröge
1Centre for Musculoskeletal Surgery, Charité - University Medicine Berlin, Augustenburger Platz 1, 13353, Berlin, Germany, clemens.gwinner@charite.de.
Purpose:
The incidence of periprosthetic fractures is inevitably increasing. Sufficient stabilisation and proper screw placement next to large-volume implants remains difficult. Modern locking plates allow polyaxial, thus bicortical, screw placement around a prosthetic stem. This study analysed the biomechanical properties of different screw configurations in a locking plate construct of a periprosthetic femoral fracture model.
Methods:
A total of 20 Sawbones were used to stabilise a Vancouver-B1 femoral fracture with a locking plate using either four monocortical screws or three bicortical screws for proximal fixation. These were loaded with an increasing axial compression until failure.
Results:
Bicortical screw purchase was significantly superior to monocortical regarding load to failure (1,510 N ± 284 N versus 2,350 N ± 212 N, p < 0.001) and maximal number of cycles (6803 ± 760 versus 4041 ± 923, p < 0.001). However, the mode of failure in the bicortical group was a severe comminuted fracture pattern as opposed to the monocortical group in which a pull-out of the screws without further damage to the bone was observed.
Conclusions:
Bicortical screw placement enhances the primary stability in treating periprosthetic femoral fractures. Notably, the mode of failure may limit the salvage options in case of revision surgery.
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