Related Experiment Video
Updated: Apr 12, 2026
09:56
In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
10.1K
Bilateral Subretinal Fluid Mimicking Subretinal Neovascularization Within 24 Hours After Selective Laser
Charles A Phillis1, Robert D Bourke
1*Griffith University School of Medicine, Gold Coast †Vision Eye Institute, Coolangatta, Qld, Australia.
Journal of Glaucoma
|May 8, 2015
Summary
Selective laser trabeculoplasty (SLT) can cause subretinal fluid and vision loss, a new finding in glaucoma treatment. This complication, though rare, necessitates awareness due to potential long-term visual impairment.
Area of Science:
- Ophthalmology
- Glaucoma Management
- Retinal Diseases
Background:
- Selective laser trabeculoplasty (SLT) is a common, safe glaucoma treatment.
- SLT is thought to induce an inflammatory response.
- Previous reports of SLT complications include cystoid macular edema.
Observation:
- This study reports a novel entity: bilateral subretinal fluid (SRF) after SLT.
- SRF developed within 24 hours of bilateral SLT in open-angle glaucoma patients.
- Clinical examination, OCT, and fluorescein angiography confirmed SRF.
Findings:
- Patients experienced rapid, bilateral vision loss post-SLT.
- Optical coherence tomography showed increased macular thickness due to SRF.
- Fundus fluorescein angiography revealed subfoveal leakage, with SRF resolving in 4 days.
- Best corrected visual acuity was decreased long-term.
Implications:
- The findings suggest a causal link between SLT and SRF development.
- This complication may result from an intraocular inflammatory cascade.
- Clinicians and patients should be aware of this new SLT complication and its potential for permanent visual changes.
