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Editorial commentary: ACL tissue bioengineering clinical application is in its infancy
Summary
Tissue engineering for anterior cruciate ligament (ACL) repair shows promise with cells, scaffolds, and growth factors. Adding a structural tie could overcome initial scaffold weakness for better clinical outcomes.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Orthopedic Surgery
Background:
- Preclinical studies show promise for anterior cruciate ligament (ACL) tissue engineering using cells, scaffolds, growth factors, and stimulation.
- Current clinical applications of ACL tissue engineering are limited.
- Bioactive scaffolds often exhibit insufficient mechanical strength at the initial stage (time zero).

