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Updated: Apr 12, 2026

A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
Published on: June 15, 2018
Optimizing diagnostic testing for Clostridium difficile: The perceptions of physicians and nurses on when to order
Rebekah Blakney1, Eric Yanke2, Cory Fink3
1Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI; Department of Population Health Sciences, University of Wisconsin-Madison, Madison, WI.
Physicians and nurses disagree on key risk factors for ordering Clostridium difficile diagnostic tests. Further research is needed to understand these differences in clinical decision-making for C. diff testing.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Healthcare Management
Background:
- Clostridium difficile infection (CDI) is a significant healthcare-associated pathogen.
- Accurate and timely diagnostic testing is crucial for effective CDI management and infection control.
- Clinical decision-making for ordering CDI tests involves assessing various patient risk factors.
Purpose of the Study:
- To identify and compare the perceived importance of risk factors for ordering Clostridium difficile diagnostic testing among physicians and nurses.
- To investigate potential discrepancies in risk factor assessment between these two healthcare professional groups.
Main Methods:
- A survey was administered to physicians and nurses at a single hospital.
- Participants were asked to rank the importance of specific risk factors when deciding to order Clostridium difficile diagnostic tests.
Main Results:
- Both physicians and nurses considered several risk factors important for ordering Clostridium difficile diagnostic tests.
- Significant disagreement was observed between physicians and nurses regarding the relative importance of certain risk factors.
- Specific risk factors contributing to the disagreement were identified but not detailed in the abstract.
Conclusions:
- Discrepancies in the perceived importance of risk factors for Clostridium difficile diagnostic testing exist between physicians and nurses.
- These differences highlight a need for further investigation into clinical decision-making processes for CDI testing.
- Standardizing the approach to CDI testing based on evidence-based risk factors may improve diagnostic accuracy and patient care.
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