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Updated: Apr 12, 2026

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Examination of Mitotic and Meiotic Fission Yeast Nuclear Dynamics by Fluorescence Live-cell Microscopy
Published on: June 24, 2019
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The development of a nucleus staining fluorescent probe for dynamic mitosis imaging in live cells
Krishna Kanta Ghosh1, Yun-Mi Jeong, Nam-Young Kang
1Department of Chemistry & MedChem Program of Life Sciences Institute, National University of Singapore, 117543 Singapore. chmcyt@nus.edu.sg.
Abstract:
A low-toxicity nucleus staining fluorescent probe, , was developed for real time mitosis imaging in live cells. was identified by unbiased high-throughput imaging-based screening of a new xanthone library (AX). Unlike the conventional Hoechst dye, the low toxicity of allows long term monitoring of cell division over more than one cell cycle.

