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[Phyto-adaptogens--protection against stress?].

|May 13, 2015

Summary

Adaptogens enhance the body's resistance to stressors, normalizing functions without harm. This review covers their efficacy, activity, and effects on humans and animals.

Area of Science:

Pharmacology
Toxicology
Natural Products Chemistry

Context:

The concept of adaptogens originated in the former USSR, with early research primarily in Russian and Scandinavian scientific communities.
Limited English-language publications historically hindered global understanding of adaptogen research.
Recent decades have seen increased international research and English publications, particularly from Western Europe and the USA.

Purpose:

To review existing studies on adaptogens and explain their unique activity.
To explore the efficacy of adaptogen use, both in single doses and long-term.
To differentiate the effects and properties of various adaptogens.

Summary:

Adaptogens are defined as substances that increase resistance to physical, chemical, or biological noxious factors, promoting a normalizing effect on bodily functions without causing harm.

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Research indicates adaptogens can be used effectively as single doses or for long-term benefits.

The article discusses adaptogenic activity and its effects on diverse physiological functions in both human and animal models.

Impact:

Facilitates a deeper understanding of adaptogenic mechanisms and applications.
Highlights the potential of adaptogens in enhancing physiological resilience.
Provides a comprehensive overview for researchers and practitioners interested in natural approaches to stress adaptation.