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Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
Published on: February 15, 2016
G-arylated hydrogen-bonded cyclic tetramer assemblies with remarkable thermodynamic and kinetic stability
Sonia Romero-Pérez1, Jorge Camacho-García1, Carlos Montoro-García1
1Nanostructured Molecular Systems and Materials Group, Departamento de Química Orgánica, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Abstract:
The preparation and self-assembly of novel G-C dinucleoside monomers that are equipped with electron-poor aryl groups at the G-N(2) amino group have been studied. Such monomers associate via Watson-Crick H-bonding into discrete unstrained tetrameric macrocycles that arise as a thermodynamically and kinetically stabilized product in a wide variety of experimental conditions, including very polar solvent environments and low concentrations. G-arylation produces an increased stability of the cyclic assembly, as a result of a subtle interplay between enthalpic and entropic effects involving the solvent coordination sphere.
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