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Interaction between the serotonin and dopamine systems in humans: preliminary findings
P Castrogiovanni1, A Di Muro, I Maremmani
1Department of Psychiatry, University of Pisa, Italy.
Brain Research
|December 11, 1989
Abstract:
The availability of peripheral tools, such as platelet [3H]-imipramine binding and electroretinogram b-wave amplitude, for investigating serotonin and dopamine systems respectively, prompted us to explore the possible relationships between these two systems in a group of 8 healthy drug-free volunteers. The results showed a significant correlation between the peripheral parameters of serotonin and dopamine systems and underline the importance of studying different neurotransmitters at the same time in humans.