Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Stimuli-responsive protein-based films for postharvest preservation of fruits and vegetables.

International journal of biological macromolecules·2026

Same author

Black cumin (<i>Nigella sativa</i>) oleosome as a natural delivery system for curcumin: characterization, preparation, and <i>in vitro</i> digestive behavior.

Frontiers in nutrition·2026

Same author

Bidirectional Brain-Machine Communication and Neuromodulation by Supramolecular Hydrogel Neural Probes for Chronic Pain Management.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Natural Oleosomes from Nuts and Seeds: Structural Function and Potential for Pharmaceutical Applications.

Pharmaceutics·2026

Same author

Development of a Raft-Forming System Using <i>Plantago major</i> Mucilage as a Natural Polymer for Sustained Gastric Release of <i>Artemisia annua</i> L. Phenolic Extract.

Pharmaceutics·2026

Same author

Development and evaluation of alginate-based gastroretentive raft-forming systems enabling sustained release of propolis in gastric ulcer treatment.

Drug delivery·2026

Same journal

An intrinsically stretchable nanowire-based sensing patch for wearable analysis of sweat chloride ion composition.

Chemical communications (Cambridge, England)·2026

Same journal

A sterically rigid-flexible balanced NHC-Pd precatalyst for room-temperature solvent-free C-N coupling of benzocyclic amines.

Chemical communications (Cambridge, England)·2026

Same journal

Portable fluorescent conjugated microporous polymer sensor coupled with a smartphone for on-site Fe<sup>3+</sup> detection in water.

Chemical communications (Cambridge, England)·2026

Same journal

Accelerated discovery of NO<sub>3</sub>RR single-atom catalysts <i>via</i> high-throughput DFT and machine learning.

Chemical communications (Cambridge, England)·2026

Same journal

Wafer-scale robust graphene electronics under industrial processing conditions.

Chemical communications (Cambridge, England)·2026

Same journal

Subnanoscale IrW oxide anodes: breaking immiscibility for high activity and durability in water electrolysis.

Chemical communications (Cambridge, England)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 12, 2026

Use of Microscale Thermophoresis to Measure Protein-Lipid Interactions

Use of Microscale Thermophoresis to Measure Protein-Lipid Interactions

Published on: February 10, 2022

Lipase-modified pH-responsive microgel-based optical device for triglyceride sensing.

Qiang Matthew Zhang¹, Darren Berg, Samuel M Mugo

¹Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2 Canada. michael.serpe@ualberta.ca.

Chemical Communications (Cambridge, England)

|May 19, 2015

Summary

This summary is machine-generated.

Researchers developed a novel triglyceride biosensor using enzyme-loaded microgels. The optical device detects triolein concentration, showing potential for triglyceride monitoring.

More Related Videos

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

Thermal Measurement Techniques in Analytical Microfluidic Devices

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

Related Experiment Videos

Last Updated: Apr 12, 2026

Use of Microscale Thermophoresis to Measure Protein-Lipid Interactions

Use of Microscale Thermophoresis to Measure Protein-Lipid Interactions

Published on: February 10, 2022

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Microfluidic Production of Lysolipid-Containing Temperature-Sensitive Liposomes

Published on: March 3, 2020

Thermal Measurement Techniques in Analytical Microfluidic Devices

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

Area of Science:

Biomaterials Science
Chemical Engineering
Analytical Chemistry

Background:

pH-responsive polymers are crucial for developing smart materials.
Enzyme immobilization enhances biosensor stability and performance.
Poly(N-isopropylacrylamide)-based microgels offer tunable swelling properties.

Purpose of the Study:

To synthesize lipase-modified, pH-responsive poly(N-isopropylacrylamide)-based microgels.
To fabricate an optical device utilizing these microgels for triglyceride detection.
To evaluate the device's response to varying concentrations of triolein.

Main Methods:

Synthesis of pH-responsive poly(N-isopropylacrylamide)-based microgels.
Immobilization of lipase onto the microgels.
Fabrication of a sandwich-type optical device with gold layers.
Investigation of the device's optical response to triolein.

Main Results:

Successful synthesis and characterization of lipase-loaded microgels.
The optical device exhibited a concentration-dependent response to triolein.
The device demonstrated sensitivity to triglyceride levels.

Conclusions:

Lipase-modified pH-responsive microgels can be effectively used in optical biosensors.
The developed device shows promise for accurate triglyceride detection.
This technology offers a potential platform for triglyceride biosensing applications.